Retrogene

Word RETROGENE
Character 9
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Retrogene"

What do we mean by retrogene?

Here you will find one or more explanations in English for the word retrogene. Define retrogene, retrogene synonyms, retrogene pronunciation, retrogene translation, English dictionary definition of retrogene.

Synonyms and Antonyms for Retrogene

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The word "retrogene" in example sentences

In addition, the Makorin gene family counts at least 3 functional members in the mouse including, of interest, a bona fide functional retrogene, which is transcribed, conserved in mammals, and encodes the Makorin-3 protein, as well as numerous pseudogenes, which can complicate molecular and sequence analysis. ❋ Unknown (2006)

Owing to these characteristics, the researchers concluded that the extra gene is a so-called retrogene that was inserted into the dog genome some time after the ancestor of modern dog breeds diverged from wolves. ❋ Unknown (2009)

These characteristics led researchers to conclude that the extra gene is a so-called retrogene that was inserted into the dog genome some time after the ancestor of modern dog breeds diverged from wolves. ❋ Unknown (2009)

The element -- a so-called retrogene -- changes the expression of IGF-1 and gives the dogs the distinctive short, bowed forelimbs of chondrodysplasia. ❋ Unknown (2009)

There are at least seven different known instances of common retrogene insertions between chimps and humans. ❋ Unknown (2009)

Still, there were some reasons for skepticism – for instance, the Mkrn1-p1 retrogene, despite its purported crucial role in mice, is absent from the genome of all other mammals tested, including closely related rats. ❋ Unknown (2006)

There is some idea that retrogene formation may be favored in testes due to hyperactivity of transcription during male meiosis. ❋ Unknown (2005)

But in every single case, the corresponding retrogene was expressed in testes only. ❋ Unknown (2005)

VonHoldt BM, Quignon P, Margulies EH, Shao S, et al. (2009) An expressed fgf4 retrogene is associated with breed-defining chondrodysplasia in domestic dogs. ❋ Danika Bannasch Et Al. (2010)

In case of short-legged dogs, the inserted retrogene results in the overproduction of the FGF4 protein, which according to researchers could turn on key growth receptors at the wrong times during foetal development. ❋ Unknown (2009)

The dog findings are the first example of a retrogene that has spurred significant and long-lasting variation within a single species. ❋ Unknown (2009)

The retrogene is found in so many of these small dogs that Ostrander thinks it inserted into the genome of a common ancestor before the dogs separated into 20 different breeds or so. ❋ Unknown (2009)

In the case of short-legged dogs, the inserted retrogene results in the overproduction of the FGF4 protein, which researchers hypothesize may turn on key growth receptors at the wrong times during fetal development. ❋ Unknown (2009)

However, the dog findings are the first example of a retrogene that has spurred significant and long-lasting variation within a single species. ❋ Unknown (2009)

"We were surprised to find that just one retrogene inserted at one point during the evolution of a species could yield such a dramatic physical trait that has been conserved over time." ❋ Unknown (2009)

We were surprised to find that just one retrogene inserted at one point during the evolution of a species could yield such a dramatic physical trait that has been conserved over time, "said the study's first author, DR. ❋ Unknown (2009)

Cross Reference for Retrogene

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What does retrogene mean?

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