Salmeterol

Some Beta-2 agonists have a slower onset of action but a longer period of activity, such as salmeterol xinafoate, and formoterol fumarate. ❋ Unknown (2009)

(termed B16 Arg/Arg) benefit less from treatment with long-acting beta-2 agonists such as salmeterol and inhaled corticosteroids than do those with two genes coding for amino acid glycine (termed B16 Gly/Gly) at this position. ❋ Unknown (2009)

Big Pharma and the FDA have known for years that formoterol fumarate, found in Symbicort, Dulera and Foradil, and salmeterol, found in Advair Diskus and Serevent Diskus, can paradoxically cause asthma deaths, especially in children and African-Americans. ❋ Martha Rosenberg (2011)

Ziering conducted trials on salmeterol the LABA, Flonase and other respiratory drugs and wrote medication-friendly papers like Allergic rhinitis. ❋ Martha Rosenberg (2011)

In one study, conducted at Vivra and elsewhere, more than 40 percent of people on Singulair and salmeterol the LABA in Advair had adverse events, two withdrew with -- anybody? ❋ Martha Rosenberg (2011)

In fact, salmeterol, the drug in Advair and Serevent, is considered so unsafe, a huge trial called the Salmeterol Multi-center Asthma Research Trial, or SMART was terminated in 2003 after there were 16 deaths, 44 intubations and 369 hospitalizations on LABAs, mostly in African-Americans 16 deaths, 44 intubations. ❋ Martha Rosenberg (2011)

The new FDA restrictions apply to four drugs: salmeterol  (Serevent) and formoterol (Foradil), which contain only an LABA, and the combination medications, salmeterol/fluticasone (Advair) and formoterol/budesonide (Symbicort), which contain both a LABA and an inhaled corticosteroid. ❋ Unknown (2010)

The new FDA restrictions apply to four drugs: salmeterol(Serevent) and formoterol (Foradil), which contain only an LABA, and the combination medications, salmeterol/fluticasone (Advair) and formoterol/budesonide (Symbicort), which contain both a LABA and an inhaled corticosteroid. ❋ Unknown (2010)

Of the patients who received salmeterol, one was withdrawn because of insomnia, two were withdrawn because of worsening asthma, and one died as a result of bronchial asthma. ❋ Unknown (2009)

Most people do not exercise more than once daily, and one or two inhalations of a short-acting beta-agonist is effective at a fraction of the cost of salmeterol and montelukast. ❋ Unknown (2009)

Five patients were withdrawn from the study because of a clinical adverse event (four in the salmeterol group and one in the montelukast group). ❋ Unknown (2009)