A recent study revealed that resistance by the malaria parasite to pyrimethamine and sulphadoxine drug combination, was widespread, and far more so than previously thought. ❋ Unknown (2003)
Many countries then averted to using sulphadoxine-pyrimethamine (SP), also known as Fansidar, but resistance to that is also spreading. ❋ Unknown (2002)
- Pyrimethamine-sulphadoxine (Fansidar) · Tablet with 500 mg of sulphadoxine + 25 mg of pyrimethamine, orally ❋ Unknown (1993)
· Ampoule with 200 mg of sulphadoxine + 10 mg of pyrimethamine/ml ❋ Unknown (1993)
Two thousand four hundred and fifty-one children aged 3-59 months were randomly allocated to four groups to receive: three days of artesunate plus amodiaquine (AS+AQ) monthly, three days of AS+AQ bimonthly, one dose of sulphadoxine-pyrimethamine (SP) bi-monthly or placebo. ❋ Lesong Conteh Et Al. (2010)
IPTc with sulphadoxine-pyrimethamine (SP) plus artesunate (AS), SP plus three daily doses of amodiaquine (AQ) or SP alone is an efficacious and safe intervention for reducing the burden of malaria in children in high transmission areas with short transmission periods ❋ Lesong Conteh Et Al. (2010)
Shulman CE, Dorman EK, Cutts F, Kawuondo K, Bulmer JN, et al. (1999) Intermittent sulphadoxine-pyrimethamine to prevent severe anaemia secondary to malaria in pregnancy: a randomised placebo-controlled trial. ❋ Ricardo Águas Et Al. (2009)
Malar J 6: 88. van Eijk AM, Ayisi JG, ter Kuile FO, Otieno JA, Misore AO, et al. (2004) Effectiveness of intermittent preventive treatment with sulphadoxine-pyrimethamine for control of malaria in pregnancy in western Kenya: a hospital-based study. ❋ Ricardo Águas Et Al. (2009)
A change in chemotherapy is likely to have played a substantial role - until 2004, chloroquine alone was mainly used but as parasite resistance to this drug had increased to high levels, the first-line treatment of choice became sulphadoxine plus pyrimethamine (SP) combined with chloroquine, from early 2005 onwards. ❋ Unknown (2008)
Mixed methods including a rapid qualitative assessment and quantitative health facility survey were used to investigate communities 'and providers' knowledge and practices relating to malaria, EPI, sulphadoxine-pyrimethamine and existing health posters. ❋ Unknown (2008)
Intermittent preventive treatment of malaria in infants (IPTi) using sulphadoxine-pyrimethamine and linked to the expanded programme on immunization (EPI) is a promising strategy for malaria control in young children. ❋ Unknown (2008)
Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) reduces the incidence of malaria episodes in young children. ❋ Unknown (2008)
Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP) is recommended for reducing the risk of malaria in pregnancy and its consequences on mothers and babies ❋ Henriette Delenne Piero L Olliaro (2008)
Intermittent preventive treatment with sulphadoxine-pyrimethamine for pregnant women ❋ Unknown (2008)
