Thiazolidinedione

Word THIAZOLIDINEDIONE
Character 17
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Thiazolidinedione"

What do we mean by thiazolidinedione?

A class of drugs used to treat type 2 diabetes by decreasing insulin resistance. noun

Any of a class of drugs, used to treat diabetes, containing a five-membered heterocyclic ring containing a nitrogen and a sulfur atom and two carbonyl groups. noun

Here you will find one or more explanations in English for the word thiazolidinedione. Define thiazolidinedione, thiazolidinedione synonyms, thiazolidinedione pronunciation, thiazolidinedione translation, English dictionary definition of thiazolidinedione.

Synonyms and Antonyms for Thiazolidinedione

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The word "thiazolidinedione" in example sentences

Another recent study suggests that diabetics who are being treated with thiazolidinedione, an antidiabetic drug, provided “further evidence of a possible association between long-term use of thiazolidinediones and fractures, particularly of the hip and wrist, in patients with diabetes mellitus.” ❋ M.D. Nicholas Perricone (2010)

The Committee points out that Dr Buse is an expert in diabetes with extensive research experience in the thiazolidinedione class of drugs that includes Avandia and states: "Corporate intimidation, the silencing of scientific dissent, and the suppression of scientific views threaten both the public well-being and the financial health of the federal government, which pays for health care." ❋ Unknown (2008)

On December 12, 2007, JAMA reported another population-based study by Canadian researchers of patients 66 and older with diabetes, that found thiazolidinedione treatment, primarily with Avandia, was associated with an increased risk of congestive heart failure, acute myocardial infarction, and mortality when compared with other combination oral hypoglycemic agent treatments. ❋ Unknown (2008)

Unfortunately, as the head of one endocrinology department at a leading university medical school put it to me, an alarming number of patients are dropping out of ongoing clinical trials involving rosiglitazone and other thiazolidinedione drugs thanks to the media and congressional circus over Avandia. ❋ Unknown (2008)

After factoring in the potential effects of other risk factors, the investigators found that the use of any thiazolidinedione was associated with a 59% increased risk of cancer, but there was an 89% increased risk associated with Avandia. ❋ Unknown (2007)

"This suggests that thiazolidinedione treatment is a risk factor and can contribute to excess incidence of fractures in diabetes," the researchers wrote in the study. ❋ Unknown (2007)

Bear Stearns analyst Mark Schoenebaum said physicians whom Bear Stearns spoke with "were not shy about discussing their off-label use of Byetta," particularly with thiazolidinedione, or TZD. ❋ Unknown (2006)

It is indicated for the treatment of type 2 diabetes as a monotherapy and in combination with metformin, a sulphonylurea, a thiazolidinedione or insulin. ❋ Unknown (2012)

Pioglitazone is a thiazolidinedione or TZD, marketed by Takeda as ACTOS

Part D prescription drug plan from July 2006-June 2009 and who underwent follow-up for up to 3 years after thiazolidinedione initiation. ❋ D. J. (2010)

Objective To determine if the risk of serious cardiovascular harm is increased by rosiglitazone compared with pioglitazone, the other thiazolidinedione marketed in the United States. ❋ D. J. (2010)

As per the study's results, after taking a thiazolidinedione (TZD) for one year, women are 50 percent more likely to have a bone fracture than patients not taking TZDs. ❋ Unknown (2010)

The second drug candidate DB959 is a highly selective, non-thiazolidinedione (TZD), first-in-class dual PPAR (peroxisome proliferator activated receptor) delta/gamma agonist in development for type 2 diabetes. ❋ Unknown (2010)

As per the study's results, after taking a thiazolidinedione (TZD) for one year, women are ❋ Ani (2010)

The safety of the blood-sugar-lowering drug, part of the thiazolidinedione family, has been in question for years. ❋ Unknown (2010)

Avandia is an anti-diabetic drug in the thiazolidinedione class of drugs. ❋ Steve Busfield (2010)

BYETTA provides sustained A1C control and low incidence of hypoglycemia when used alone or in combination with metformin or a thiazolidinedione, with potential weight loss. ❋ Unknown (2010)

The researchers studied 4,511 patients who filled at least one prescription for a thiazolidinedione between 2000 and 2007 at Henry Ford Hospital. ❋ Unknown (2010)

Cross Reference for Thiazolidinedione

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What does thiazolidinedione mean?

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