Thromboxanes

Decrease production of inflammatory chemicals called thromboxanes and leukotrienes. ❋ M.D. Leo Galland (2011)

Corey's most important total syntheses concern the medically very important eicosanoids such as prostaglandins, prostacyclins, thromboxanes and leucotrienes, which occur naturally in extremely small quantities. ❋ Unknown (1990)

This has led to the discovery of endoperoxides, thromboxanes and the leukotrienes, and my group has mainly been involved in studying the chemistry, biochemistry and biology of these compounds and their role in biological control system. ❋ Unknown (1983)

In the last few years compounds have been developed, which effectively and selectively block the formation of thromboxanes in the platelets. ❋ Unknown (1982)

In one of them the cyclic endoperoxides constitute an important branching point from which the stable prostaglandins as well as the more unstable thromboxanes and prostacyclin are formed. ❋ Unknown (1982)

The thromboxanes in the platelets initiate an aggregation of blood cells while the prostacyclin in the vessel wall effectively inhibits such ❋ Unknown (1982)

Samuelsson's discoveries of the endoperoxides, thromboxanes and leukotrienes were crucial for our present understanding of the biological significance of this system. ❋ Unknown (1982)

In contrast to the prostaglandins as well as thromboxanes and prostacyclin the leukotrienes do primarily not act as defense hormones. ❋ Unknown (1982)

In addition, Vane has made the fundamental discovery that antiinflammatory compounds such as aspirin act by blocking the formation of prostaglandins and thromboxanes. ❋ Unknown (1982)

The metabolites of the endoperoxides (the stable prostaglandins, the thromboxanes and prostacyclin) haye been called defense hormones. ❋ Unknown (1982)

Mast cell mediators including (PP-LT): prostaglandins (PG), prostacyclins (PGI), leukotrienes (LT) and thromboxanes (TX). ❋ Unknown (2008)

PP-LT): prostaglandins (PG), prostacyclins (PGI), leukotrienes (LT) and thromboxanes ❋ Unknown (2008)