That was very simple — by using an enzyme that can read DNA and synthesise RNA, called a transcriptase, he added. ❋ Unknown (2005)
One example is reverse transcriptase, which is a viral enzyme involved in the infection of cells by telomeres. ❋ Unknown (2009)
The cell culture supernatant was regularly tested for reverse transcriptase activity. ❋ Unknown (2009)
My project analysed the use of a synthetic molecule which inhibited the reverse transcriptase to control leukaemia induced by Friend virus. ❋ Unknown (2009)
Combining both protein and RNA components, telomerase is a reverse transcriptase which adds telomere DNA to the ends of molecules using an RNA template. ❋ Unknown (2009)
The first week of sampling did not show any reverse transcriptase activity, but in the second week I detected weak enzymatic activity, which increased significantly a few days later. ❋ Unknown (2009)
The reverse transcriptase activity level dropped dramatically however, as the T lymphocytes in the culture were dying. ❋ Unknown (2009)
Furthermore, a member of this lab had been in our group teaching us the technique for the detection of reverse transcriptase, soon after the discovery of this enzyme by David Baltimore and Howard Temin. ❋ Unknown (2009)
This idea proved successful, and as we had hoped, the virus − which was still present in the cell culture − started to infect the newly added lymphocytes and we were soon again able to detect significant reverse transcriptase activity. ❋ Unknown (2009)
[AS] As you mentioned, telomerase, was a novel sort of DNA-synthesizing enzyme; it's a reverse transcriptase, containing both protein and RNA. ❋ Unknown (2009)
Indeed, Howard Temin and Mizutani, and independently David Baltimore, discovered in 1970 a specific enzyme associated with Rous sarcoma virus (RSV), the reverse transcriptase (RT), capable of reversely transcribing the viral RNA into DNA. ❋ Unknown (2009)
We had previously detected mouse mammary tumour virus (MMTV) sequences in the lymphocytes of breast cancer patients, and we were familiar with the technique of reverse transcriptase activity detection. ❋ Unknown (2009)
Results from analysis of the gene sequence, reverse transcriptase PCR, and enzyme assays indicated that dntD dntE ORF13 dntG composes an operon that encodes the lower pathway. ❋ Unknown (2010)
This synthetic molecule, named HPA23, proved capable of inhibiting reverse transcriptase activity of Friend virus in culture. ❋ Unknown (2009)
The drug, Edurant, belongs to a class of HIV drugs called non-nucleoside reverse transcriptase inhibitors and works to block HIV viral replication. ❋ Jennifer Corbett Dooren (2011)
In 1970, when Temin and Baltimore had discovered reverse transcriptase, Weinberg was still at the bench, laboriously purifying genes out of monkey viruses. ❋ Siddhartha Mukherjee (2010)
Reverse transcriptase: An enzyme that converts a chain of RNA into a chain of DNA. ❋ Siddhartha Mukherjee (2010)
Retrovirus: an RNA virus that keeps its genes in the form of RNA and is capable, by virtue of an enzyme, reverse transcriptase, to convert its genes from the RNA form into a DNA form. ❋ Siddhartha Mukherjee (2010)
It's a nucleoside reverse transcriptase inhibitor, or an NRTi, in AIDS speak. ❋ Charles Karel Bouley (2010)
