Tyrosinase

It actually helps block an enzyme called tyrosinase which is needed to make melanin. ❋ Unknown (2008)

Hydrogen peroxide attacks an enzyme called tyrosinase, which starts the production of melanin. ❋ Unknown (2009)

The gene alters the amino acid tyrosinase which is a necessary building block for the proteins that pigment hair and skin. ❋ Field Notes (2006)

Not only that, but high levels of hydrogen peroxide and low levels of MSR A and B disrupt the formation of yet another enzyme, called tyrosinase, that leads to the production of hair pigments. ❋ Ewillett (2009)

It includes tyrosinase activity (melanin is synthesed from tyrosine), DOPA production (used in threatment of Parkinson disease and depression) and in many other metabolytical pathways. ❋ Unknown (2010)

It works by blocking the enzyme tyrosinase inside the melanocytes that makes melanin. ❋ Ellen Marmur (2009)

The first step of the synthetic pathway for both eumelanins and pheomelanins is mediated by tyrosinase: ❋ Unknown (2006)

It was a surprise that the T cells of some melanoma patients recognized antigens in normal proteins -- a situation that verges on an auto-immune response; Boon's group has found two of these antigens in melanoma, Melan-A and tyrosinase. ❋ Unknown (1997)

It is an essential element, being part of enzymes like tyrosinase, cytochrome oxidase, etc. ❋ Unknown (1996)

In addition, preclinical data indicate that OXi4503 is metabolized by oxidative enzymes e.g., tyrosinase and peroxidases, which are elevated in many solid tumors and tumor white blood cell infiltrates, to an orthoquinone chemical species that has direct cytotoxic effects on tumor cells.

People with a type of albinism - OCA1 - have light skin, white hair and light irises caused by defective tyrosinase genes which mean they struggle to produce melanin. ❋ Unknown (2011)

Genetic testing for tyrosinase and other genes in the study could determine the best candidates for melanoma-fighting immunotherapies, such as interleukin 2 and various vaccines, he noted. ❋ MedPageToday.com - Medical News Plus CME For Physi (2010)

This gene encodes tyrosinase, the key enzyme in melanocytes that synthesizes melanin and which is the major target of autoimmunity in generalized vitiligo. ❋ MedPageToday.com - Medical News Plus CME For Physi (2010)