Upregulation

Word UPREGULATION
Character 12
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Upregulation"

What do we mean by upregulation?

The process, in the regulation of gene expression, in which the number, or activity of receptors increases in order to increase sensitivity

Synonyms and Antonyms for Upregulation

  • Synonyms for upregulation
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  • Antonyms for upregulation
  • Upregulation antonyms not found!

The word "upregulation" in example sentences

The researchers also found that social factors, in the form of chemical signals called pheromones, induced this "upregulation" of for. ❋ Unknown (2008)

The researchers also found that social factors, in the form of chemical signals called pheromones, induced this "upregulation" of the gene. ❋ Unknown (2008)

As exciting as these particular discoveries are, the upregulation of the production of HO-1 is just one of many ways that nitrolinoleic acid provides protection to our bodies. ❋ M.D. Nicholas Perricone (2010)

The most exciting action of nitrolinoleic acid, in my opinion, is the upregulation of NRF2, which, as you know, is hugely important, as it protects cells from oxidative stress free-radical damage and subsequent inflammation. ❋ M.D. Nicholas Perricone (2010)

Given that DA depletion in rats can induce a reduction in the DA transporter and an upregulation of D2/D3 receptors, our data are consistent with the hypothesis that major depression is associated with a deficiency of mesolimbic DA. ❋ Unknown (2006)

Therefore, the present data suggest that upregulation of interferon response genes is not, as commonly assumed, required for sustained disease. ❋ Malgorzata Romanowska Et Al. (2010)

Importantly, wild type C57Bl/6 mice administered GW501516 did not exhibit these changes (table S1), but did show the expected upregulation of genes involved in lipid metabolism (table S5), thereby confirming that the observed induction of IL1-signalling was triggered by the transgene rather than endogenous murine PPARβ/δ. ❋ Malgorzata Romanowska Et Al. (2010)

Thus, upregulation of PPARβ/δ appears to occur downstream of individually variable genomic risk, offering a potential target for treatment relevant for most patients. ❋ Malgorzata Romanowska Et Al. (2010)

Furthermore, while the upregulation of IFN response genes could be taken for granted in the milieu of a wound-response, our data show that they should actually be repressed by the so-called anti-inflammatory response mediated by STAT3 ❋ Malgorzata Romanowska Et Al. (2010)

As CCL20 is activated by Th17 cytokines, the upregulation of CCL20 production by Trim32 provides a positive feedback loop of CCL20 and Th17 activation in the self-perpetuating cycle of psoriasis. ❋ Yuangang Liu (2010)

As shown in figure 1a, both data sets confirm highly significant upregulation of PPARβ/δ in psoriatic skin whereas both PPARα and PPARγ are downregulated, consistent with the notion that PPARβ/δ acts antagonistically to PPARγ in psoriasis, as previously proposed ❋ Malgorzata Romanowska Et Al. (2010)

Degradation of high-molecular-weight kininogen and upregulation of the bradykinin-1 receptor in inflamed tissues indicated activation of the contact system in 11 patients. ❋ Adam Linder (2010)

Effects of yellow intraocular lenses on light-induced upregulation of vascular endothelial growth factor. ❋ Unknown (2010)

Their continuous upregulation despite STAT3 activation suggests the existence of as yet to be identified factors actively inhibiting STAT3 repression of IFN target genes (schematically shown in fig. 6f). ❋ Malgorzata Romanowska Et Al. (2010)

In this regard, too, the upregulation of PPARβ/δ is notable since it is an important regulator of the wound response ❋ Malgorzata Romanowska Et Al. (2010)

Besides keratinocyte biology, psoriasis is marked by complex pattern of immune system activation, including expansion of CD11c, upregulation of interferon signalling, and influx of T cells. ❋ Malgorzata Romanowska Et Al. (2010)

Cross Reference for Upregulation

What does upregulation mean?

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