Uridine

Repligen announced on Monday that a mid-stage clinical trial showed one that its drug, RG2417, also known as uridine, was not significantly better than a placebo in treating bi-polar depression. ❋ Unknown (2011)

Other sugar nucleotides such as uridine diphosphate acetylglucosamine and guanosine diphosphate mannose were also isolated. ❋ Unknown (1971)

Click 'show compounds' in the right-hand nav and you should see compounds like pyrazine/uridine highlighted in the text. ❋ Egon Willighagen (2009)

Compared to human milk, cow's milk has lower levels of nucleotide as uridine, inosine, and cytidine. ❋ Unknown (2008)

Reichard repeated and extended this experiment with U-14C uridine in 1957 with much the same result for the deoxycytidine and thymidine4. ❋ Unknown (2005)

Brown made an important contribution to the Stadtman effort when he and a colleague discovered that a regulatory enzyme in the glutamine synthetic pathway was controlled by covalent attachment of a nucleotide, uridine. ❋ Unknown (1986)

Further work showed that uridine diphosphate glucose is involved in glycogen synthesis and adenosine diphosphate glucose in that of starch. ❋ Unknown (1971)

With his early collaborators, Ranwel Caputto, Carlos E. Cardini, Raúl Trucco and Alejandro C. Paladini work was started on the metabolism of galactose which led to the isolation of glucose 1,6-diphosphate and uridine diphosphate glucose. ❋ Unknown (1971)

Coadministration of ISENTRESS with drugs that are strong inducers of uridine diphosphate glucuronosyltransferase UGT 1A1 may result in reduced plasma concentrations of raltegravir.

PSI-7977 is an oral uridine nucleotide analog polymerase inhibitor of HCV. ❋ Unknown (2010)

With the exception of sequences rich in adenosine and uridine in either of these two domains, these analyses did not reveal any bias towards higher cleavage levels. ❋ Michel V. L�vesque Et Al. (2010)

Repligen granted Notice of Allowance covering use of uridine for treatment of bipolar disorder ❋ Unknown (2010)

Each minicircle consists of four constant regions interspersed by variable sequences that contain guide RNA genes required for uridine insertion/deletion RNA editing ❋ Mariana M. Hecht Et Al. (2010)

We are currently enrolling a Phase 2b clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar depression at 19 clinical sites in the United States. ❋ Unknown (2010)

At mRNA position − 4, O4 of the uridine base forms a hydrogen bond to the phosphate of nucleotide A1507 of 16SRNA. ❋ Lasse B Jenner (2010)